Receptor Tyrosine Kinases: Family and Subfamilies

Receptor Tyrosine Kinases: Family and Subfamilies

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This book devotes a chapter to each RTK family and the multiple receptors within each family, thoroughly covering all of the RTKs. The chapters all follow the same structure, presenting this essential information in an accessible and user-friendly format. Each chapter covers one specific family of receptors and begins with a general introduction to that family and a comprehensive discussion of that receptora€™s family in development and human disease. Following are in-depth analyses of each familya€™s receptors with discussions on the gene, protein, ligands, activation, and signaling pathways along with discussion of receptor processing and signal attenuation. Further, cross talk with other receptors systems, post-translational modification and specific unique characteristics to each RTK are discussed. Because it isolates and explains each family, this book is an essential companion volume to Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease, by the same authors, which talks about RTKs more generally and without the family-by-family detail.... sea urchin) Ryk. Amino acid sequences (single letter code) were aligned and gaps (-) were introduced to ... W.P.H TV Q W RLV GF FL LLL LE GAR CLANPa#39;s N S P G IN N N N. - - - - - - - - - - M L PEAED P o Es ERRRRG KEIP c Fc Lw cw w PLL. .... His LG I wH K DLATRN cREDEE---s Yw K.I.cDa#39;s AL K T K G ACT LRT Hol vs LATORa#39;s six v AHIH KYR I whilda#39;IAARN cli.I.E.E. v ... NC P DEL F.A. V. M A CCW AL D PE E RP KF Q Q L.V. Q.C. L. T. E. F. H.S.A.L. G.A.Y. RL QQ Pin N.C. P. D.anbsp;...

Title:Receptor Tyrosine Kinases: Family and Subfamilies
Author: Deric L. Wheeler, Yosef Yarden
Publisher:Springer - 2015-07-31

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